Pre-Ramadan Evaluation in Diabetes: Preparing the Patient for Safe and Meaningful Fasting
Pre-Ramadan Evaluation in Diabetes: Preparing the Patient for Safe and Meaningful Fasting
A Comprehensive Clinical Review
Dr Neeraj Manikath , claude.ai
Abstract
Ramadan fasting presents unique
challenges for patients with diabetes, requiring meticulous pre-Ramadan
evaluation and personalized management strategies. This comprehensive review
synthesizes evidence-based approaches with practical clinical pearls derived
from decades of real-world experience. We explore risk stratification
frameworks, medication adjustments, glycemic monitoring strategies, and patient
education techniques essential for safe fasting. Special emphasis is placed on
bedside nuances often overlooked in standard guidelines, including cultural
competence, individualized decision-making, and management of special
populations. The goal is to empower clinicians to conduct thorough pre-Ramadan
consultations that balance religious observance with metabolic safety,
ultimately reducing hypoglycemia, hyperglycemia, and acute complications during
this sacred month.
Keywords: Ramadan fasting, diabetes mellitus, risk
stratification, hypoglycemia, medication adjustment, cultural competence,
patient education
Introduction
Ramadan, the ninth month of the
Islamic lunar calendar, involves fasting from dawn to sunset for approximately
29-30 days. Over 1.8 billion Muslims worldwide observe this pillar of Islam,
including an estimated 50 million individuals with diabetes.1,2 While Islamic
law exempts those with illness from fasting, many patients with diabetes choose
to fast despite medical risks, driven by profound religious conviction and
community belonging.
The metabolic challenges are
formidable. Prolonged fasting durations (12-18 hours depending on geography and
season), abrupt dietary pattern changes, and altered medication timing create a
perfect storm for dysglycemia. The landmark EPIDIAR study demonstrated stark
realities: a 4.7-fold increase in severe hypoglycemia and 7.5-fold increase in
severe hyperglycemia among fasting individuals with type 1 diabetes.3 Even in
type 2 diabetes, hypoglycemia increased 7.5-fold.
Clinical
Pearl #1: The pre-Ramadan consultation is not a single encounter
but an ongoing dialogue. Initiate discussions 6-8 weeks before Ramadan to allow
adequate time for medication titration, self-management education, and
iterative decision-making. Patients who receive structured pre-Ramadan
education have 50% fewer hypoglycemic events.4
Understanding the Clinical Context
Physiological Changes During Ramadan Fasting
During the fasting state,
hepatic glycogenolysis maintains euglycemia for the first 8-12 hours, followed
by gluconeogenesis and progressive insulin reduction. In healthy individuals, counter-regulatory
hormones (glucagon, cortisol, growth hormone, epinephrine) prevent
hypoglycemia. However, patients with diabetes—especially those on insulin or
sulfonylureas—lack this physiological safety net.
Post-iftar (sunset meal)
hyperglycemia is equally problematic. Patients often consume carbohydrate-rich
foods rapidly after 14-16 hours of fasting, overwhelming insulin secretion or
exogenous insulin dosing. This is compounded by reduced physical activity and
nocturnal snacking before suhoor (pre-dawn meal).
Bedside
Hack #1: Ask patients to describe their typical Ramadan day
hour-by-hour during the initial consultation. Note wake times, prayer
schedules, meal composition, family dynamics, and occupational demands. This
granular understanding reveals individualized risk factors invisible in
standardized questionnaires. For instance, a construction worker fasting in
July faces vastly different risks than an office worker fasting in December.
Cultural and Religious Dimensions
Effective pre-Ramadan counseling
demands cultural humility. Many patients perceive medical advice against
fasting as culturally insensitive or spiritually dismissive. Frame discussions
collaboratively: "How can we work together to make fasting as safe as
possible?" rather than "You should not fast."
Understand that patients may
fast despite high-risk categorization. Rather than abandoning these patients,
intensify monitoring and provide harm-reduction strategies. Respect the
decision while ensuring informed consent about risks.
Clinical
Pearl #2: Partner with local religious leaders or hospital
chaplains familiar with Islamic jurisprudence. Many patients trust spiritual
guidance. Having an Imam affirm that "breaking fast for medical reasons is
not only permitted but obligatory" can profoundly influence patient
decisions. Some centers successfully use joint medical-religious counseling
sessions.5
Risk Stratification: The Foundation of Pre-Ramadan Assessment
The International Diabetes
Federation (IDF) and Diabetes and Ramadan (DAR) International Alliance have
developed evidence-based risk stratification categories: very high, high,
moderate, and low risk.6,7 However, applying these categories requires clinical
judgment beyond checkbox criteria.
Very High-Risk Category
Patients in this category should
be strongly advised against fasting:
•
Severe hypoglycemia or diabetic ketoacidosis within 3
months prior to Ramadan
•
Recurrent hypoglycemia or hypoglycemia unawareness
•
Poorly controlled type 1 diabetes (HbA1c >9%)
•
Advanced chronic kidney disease (eGFR <30
ml/min/1.73m²)
•
Acute illness, pregnancy (particularly first and third
trimesters), or breastfeeding
•
Cognitive impairment preventing self-management
•
Patients performing high-risk physical labor (e.g.,
driving, operating heavy machinery)
Oyster
#1 (Hidden Gem): The "3-month rule" for hypoglycemia is
not arbitrary. Studies show hypoglycemia begets hypoglycemia through defective
counter-regulation. A patient with severe hypoglycemia 4 months ago who has
been stable since may cautiously attempt fasting with intensive monitoring, but
one with an event 6 weeks ago remains high-risk despite superficial stability.
Recency matters more than frequency in some cases.8
High-Risk Category
These patients can fast with
intensive monitoring and medication adjustment:
•
Type 1 diabetes with reasonable control (HbA1c 7-9%)
•
Type 2 diabetes on intensive insulin regimens (e.g.,
basal-bolus)
•
Moderate chronic kidney disease (eGFR 30-45
ml/min/1.73m²)
•
Well-controlled diabetes with significant comorbidities
(stable coronary artery disease, heart failure)
•
Elderly patients (>75 years) even with good glycemic
control
Bedside
Hack #2: For high-risk patients who insist on fasting, negotiate
"trial fasting days" 4-6 weeks before Ramadan while on modified
medication regimens. Simulate the fasting schedule on weekends with close
glucose monitoring. If the patient experiences hypoglycemia <70 mg/dL or
symptoms, use this as a teachable moment. Real-world data beats theoretical
risk discussions.
Moderate and Low-Risk Categories
Moderate-risk patients include
those with well-controlled type 2 diabetes on metformin, DPP-4 inhibitors,
GLP-1 agonists, SGLT2 inhibitors, or low-dose sulfonylureas. Low-risk patients
have diabetes controlled by lifestyle alone or metformin monotherapy with HbA1c
<7%.
Even "low-risk"
patients require pre-Ramadan counseling. Complacency breeds complications.
Address dietary indiscretion at iftar, hydration strategies, and blood glucose
monitoring frequency.
Clinical
Pearl #3: Frailty trumps chronological age. An active 80-year-old
with diabetes on metformin alone may be lower risk than a sedentary 60-year-old
with heart failure on insulin. Use tools like the FRAIL scale or Clinical
Frailty Scale during assessment. Frail patients—regardless of age—warrant
higher risk categorization.9
Medication Management: The Art and Science
Medication adjustment is the
cornerstone of safe Ramadan fasting. The principle is simple: minimize
hypoglycemia risk without sacrificing glycemic control. The execution, however,
demands pharmacological fluency and individualization.
Oral Hypoglycemic Agents
Metformin: The safest
agent during fasting with no hypoglycemia risk. Redistribute doses: if
previously twice daily, give the larger dose at iftar and smaller at suhoor.
For extended-release formulations, switch to immediate-release for better dose
flexibility. Caution patients about gastrointestinal side effects, which may
worsen with large iftar meals.
Sulfonylureas: The
Achilles heel of Ramadan management. Gliclazide modified-release and
glimepiride are preferred over glibenclamide due to lower hypoglycemia rates.10
If a patient is on twice-daily sulfonylurea, shift to once-daily at iftar.
Reduce the total daily dose by 30-50% and monitor closely. Better yet,
transition to safer agents (DPP-4i, GLP-1 RA, SGLT2i) 6-8 weeks pre-Ramadan if
HbA1c allows.
Oyster
#2: Patients on sulfonylureas often present after Ramadan with
paradoxical HbA1c improvement despite dose reduction. Why? Elimination of
erratic eating patterns and forced portion control during iftar/suhoor create
inadvertent lifestyle modification. Use this post-Ramadan "metabolic
reset" to transition permanently to safer agents.
DPP-4 Inhibitors: Excellent
choice. Glucose-dependent mechanism minimizes hypoglycemia. No dose adjustment
needed. Continue usual regimen.
SGLT2 Inhibitors: Generally
safe but counsel patients about diabetic ketoacidosis (DKA) risk, particularly
in type 1 diabetes or insulin-deficient type 2 diabetes. Emphasize "sick
day rules"—if vomiting, abdominal pain, or profound fatigue occur, break
the fast and seek medical attention. Ensure adequate hydration between iftar
and suhoor. Consider holding SGLT2 inhibitors in patients with prior DKA or
during illness.11
GLP-1 Receptor Agonists: Ideal
for Ramadan due to low hypoglycemia risk and beneficial effects on weight and
postprandial glucose. No dose adjustment required for long-acting agents
(dulaglutide, semaglutide). For short-acting exenatide, shift both doses to
mealtimes (iftar and suhoor). Warn about nausea exacerbation with large iftar
meals.
Bedside
Hack #3: Create a "medication card" for each patient: a
wallet-sized reference showing pre-Ramadan doses, Ramadan doses, and
post-Ramadan doses. Include specific instructions ("Take glimepiride 2mg
at iftar, skip suhoor dose"). Patients find this tangible tool more useful
than verbal instructions. Laminate it so it survives the month in pockets and
purses.
Insulin Management
Insulin adjustment is nuanced
and requires patient-specific titration. General principles include:
Basal Insulin: For
once-daily basal insulin (glargine, detemir, degludec), reduce dose by 15-30%
and administer at iftar or suhoor—timing depends on individual glucose
patterns. Degludec's ultra-long action (>42 hours) offers flexibility. For
patients on NPH twice daily, switch to once-daily long-acting analog at iftar
to reduce nocturnal hypoglycemia.
Bolus Insulin: In
basal-bolus regimens, give the largest prandial dose at iftar, a smaller dose
at suhoor, and omit midday doses. Start conservatively—reduce each dose by
25-30%—then titrate based on continuous glucose monitoring (CGM) or frequent
fingerstick data. Rapid-acting analogs (lispro, aspart, glulisine) are
preferred over regular insulin for better postprandial control.
Premixed Insulin: Problematic
during Ramadan due to inflexibility. If continuation is necessary, give the
larger dose at iftar and eliminate other doses. Better approach: transition to
basal-bolus regimen 6-8 weeks pre-Ramadan for better dose individualization.
Clinical
Pearl #4: The "Rule of 70-120" for safe fasting on
insulin: Pre-suhoor glucose should be 120-180 mg/dL. If <120 mg/dL, reduce
suhoor insulin by 20%. Mid-fasting glucose (afternoon) should be >70 mg/dL.
If <70 mg/dL, break fast immediately and reduce next day's suhoor insulin by
30%. This simple protocol prevents 60-70% of severe hypoglycemic events.12
Insulin Pump and CGM Users
Continuous subcutaneous insulin
infusion (CSII) offers unparalleled flexibility. Create separate basal profiles
for fasting days: reduce basal rates by 10-40% during fasting hours, increase
slightly post-iftar to manage hyperglycemia. Bolus calculators should be
reprogrammed for new meal timings.
CGM is transformative during
Ramadan. Real-time glucose trending allows preemptive interventions before
severe dysglycemia. Set aggressive low alerts (80 mg/dL) and high alerts (200
mg/dL). Teach patients to break fasts when glucose is <70 mg/dL and trending
downward, even if asymptomatic.13
Oyster
#3: Hybrid closed-loop systems (automated insulin delivery) show
promise for Ramadan safety. Small studies demonstrate fewer hypoglycemic events
and better time-in-range compared to sensor-augmented pumps. However, these
systems require meticulous carbohydrate counting at iftar/suhoor—a challenge
when meals are communal and portions variable. Reserve for highly motivated,
tech-savvy patients.14
Glucose Monitoring and Patient Education
Self-Monitoring Blood Glucose (SMBG) Strategy
Many patients believe that
fingerstick testing "breaks the fast." Correct this misconception
early. All major Islamic jurisprudence councils permit medical testing during
Ramadan.15 Frame monitoring as an obligation to protect health, which Islam
prioritizes.
Recommended SMBG schedule for
moderate to high-risk patients:
•
Pre-suhoor (before pre-dawn meal)
•
Post-suhoor (2 hours after pre-dawn meal)
•
Midday (around 3-4 PM when hypoglycemia risk peaks)
•
Pre-iftar (just before sunset)
•
Post-iftar (2 hours after breaking fast)
Bedside
Hack #4: Teach the "Rule of 3s" for breaking fast:
glucose <60 mg/dL = break immediately; 60-70 mg/dL = recheck in 30 minutes,
break if not rising; >250 mg/dL with ketones = break fast and seek care.
Simplicity aids compliance. Write these thresholds on the medication card
mentioned earlier.
Nutritional Counseling
Partner with registered
dietitians experienced in Ramadan care. Key principles:
•
Iftar composition: Start with dates
(traditional) and water, then a balanced meal with complex carbohydrates, lean
protein, and vegetables. Avoid fried foods and concentrated sweets. The
"iftar feast" mentality drives hyperglycemia.
•
Suhoor composition: Low glycemic index foods
(oats, whole grains, legumes) sustain glucose levels during fasting. Include
protein and healthy fats. Delay suhoor as close to dawn as possible.
•
Hydration: Aggressive hydration between iftar
and suhoor (2-3 liters). Avoid caffeine and sugary drinks. Dehydration
exacerbates hyperosmolar states and increases thrombotic risk.
•
Nocturnal snacking: Discourage continuous
grazing between iftar and suhoor. If needed, one small snack with complex
carbohydrates 2-3 hours before sleep.
Clinical
Pearl #5: "Reverse dumping syndrome" post-iftar is
real. Rapid consumption of high-carbohydrate foods after prolonged fasting
causes exaggerated insulin secretion, followed by rebound hypoglycemia 2-3
hours later. Educate patients to eat slowly over 30-45 minutes, not 5 minutes.
This simple behavioral modification dramatically reduces post-iftar glucose
excursions.
Physical Activity
Exercise counseling during
Ramadan requires nuance. Vigorous exercise while fasting increases hypoglycemia
and dehydration risk. Recommend light-to-moderate activity (walking, gentle
swimming) post-iftar or 1-2 hours after suhoor. Taraweeh prayers—prolonged
standing and bowing—provide modest physical activity and should be factored
into insulin dosing.
Oyster
#4: Patients often lose weight during Ramadan but regain it
afterward. The weight loss stems from caloric restriction and altered meal
timing, not metabolic advantage. Frame Ramadan as a "metabolic boot
camp"—use it to establish healthy eating patterns and portion control that
continue post-Ramadan. This mindset shift transforms Ramadan from a temporary
disruption to a sustainable lifestyle change.
Special Populations and Clinical Scenarios
Elderly Patients
Elderly individuals face
compounded risks: polypharmacy, cognitive decline, impaired hypoglycemia
awareness, and reduced thirst perception. Even "well-controlled"
elderly patients warrant close monitoring.
Simplify regimens aggressively.
Transition complex insulin regimens to once-daily basal insulin plus safer oral
agents. Involve caregivers in monitoring and medication administration. Set
liberalized glycemic targets (HbA1c 7.5-8.5%) to prioritize safety over tight
control.
Bedside
Hack #5: Use the "teach-back" method rigorously in
elderly patients. After explaining the Ramadan plan, ask them to explain it back
to you in their own words. Cognitive screening tools (Mini-Cog, Montreal
Cognitive Assessment) help identify patients needing enhanced support. Those
scoring poorly should fast only under direct caregiver supervision.
Pregnant and Lactating Women
Pregnancy with diabetes during
Ramadan is complex. Islamic law exempts pregnant women from fasting, and
medical consensus strongly discourages it due to maternal-fetal risks.16
However, some women fast during early pregnancy before diagnosis or against
medical advice.
For those who insist, counsel
about fetal growth restriction, preterm labor, and neonatal hypoglycemia.
Insulin requirements change unpredictably. Daily monitoring by a maternal-fetal
medicine specialist is mandatory. Break fast immediately if glucose <70
mg/dL or >180 mg/dL, or if ketones are detected.
Lactating women need additional
calories (450-500 kcal/day) and fluids. Fasting may compromise milk production.
Emphasize hydration between iftar and suhoor and monitor infant weight gain.
Chronic Kidney Disease
CKD complicates Ramadan fasting
through multiple mechanisms: altered drug metabolism, volume depletion, and
electrolyte disturbances. Patients with eGFR >45 ml/min/1.73m² can usually
fast safely with adjustments. Below this threshold, individualize carefully.
Metformin is contraindicated
below eGFR 30 ml/min/1.73m². Sulfonylureas (except gliclazide) accumulate in
renal failure—avoid or reduce doses significantly. SGLT2 inhibitors lose
efficacy below eGFR 45 ml/min/1.73m² and increase DKA risk. Prefer DPP-4
inhibitors (dose-adjusted for renal function) and insulin.
Clinical
Pearl #6: Dialysis patients who fast face unique challenges.
Schedule hemodialysis sessions post-iftar when possible. Avoid excessive fluid
removal that worsens dehydration. Peritoneal dialysis patients can continue
exchanges but must adjust insulin doses in dextrose-containing dialysate.
Multidisciplinary coordination with nephrology is essential.
Cardiovascular Disease
Patients with diabetes and
established cardiovascular disease (prior MI, stroke, heart failure) are
high-risk for Ramadan complications. Dehydration increases blood viscosity and
thrombotic risk. Hypoglycemia can provoke arrhythmias and myocardial ischemia.
Counsel about warning symptoms:
chest pain, palpitations, severe dyspnea, dizziness. These mandate immediate
fast-breaking and medical evaluation. Continue cardioprotective medications
(statins, antiplatelets, ACE inhibitors) without modification. Ensure adequate
hydration to mitigate thrombotic risk.
When to Break the Fast: Clear Guidelines
Establishing clear, actionable
criteria for breaking fasts prevents ambiguity and patient hesitation. Provide
these in written form:
MANDATORY fast-breaking
criteria:
•
Blood glucose <70 mg/dL on fingerstick or CGM
•
Blood glucose >300 mg/dL, especially with ketonuria
or ketonemia
•
Hypoglycemic symptoms (tremor, sweating, confusion,
palpitations) even if glucose appears normal (glucose lag)
•
Any acute illness (fever, vomiting, diarrhea,
significant infection)
•
Dehydration symptoms (dizziness, dark urine, decreased
urine output)
•
Cardiovascular symptoms (chest pain, severe dyspnea,
palpitations)
Bedside
Hack #6: Role-play fast-breaking scenarios during the pre-Ramadan
visit. Ask: "If your glucose is 65 mg/dL at 2 PM, what do you do?"
Patients who can verbalize the correct action ("Break my fast with 15g
fast-acting carbohydrate, recheck in 15 minutes") demonstrate
understanding. Those who hesitate need more education. This active learning
cements knowledge better than passive instruction.
Oyster
#5: The "15-15 rule" works during Ramadan too: 15g
fast-acting carbohydrate (3-4 glucose tablets, 4oz juice, 1 tablespoon honey),
wait 15 minutes, recheck glucose. If still <70 mg/dL, repeat. Once >70
mg/dL and symptoms resolve, consume a snack with complex carbohydrates and
protein to prevent recurrence. Breaking a fast for hypoglycemia is not
failure—it's wisdom.
Post-Ramadan Transition: The Overlooked Phase
Pre-Ramadan counseling often
neglects post-Ramadan management. Eid al-Fitr—the festival marking Ramadan's
end—involves celebratory meals and sweets, creating hyperglycemia risk. Abrupt
return to pre-Ramadan medication doses without gradual uptitration causes
dysglycemia.
Schedule a post-Ramadan
follow-up within 1-2 weeks. Review glucose logs, assess HbA1c (if appropriate
timing), and adjust medications back to pre-Ramadan regimens or optimize based
on Ramadan performance. Some patients maintain better control during
Ramadan—leverage this success.
Clinical
Pearl #7: Use the "Ramadan report card" approach.
During post-Ramadan follow-up, review: days successfully fasted, hypoglycemic
episodes, hyperglycemic episodes, ER visits, and subjective well-being. Frame
it constructively—not as judgment, but as collaborative data review. Patients
who struggled need enhanced support for next year; those who succeeded deserve
validation and can potentially attempt fasting with less aggressive monitoring.
Building a Multidisciplinary Ramadan Diabetes Program
Optimal Ramadan diabetes care transcends
individual physician consultations. Successful programs integrate:
•
Endocrinologists/diabetologists: Lead clinical
decision-making and complex case management
•
Diabetes educators: Provide structured education
on monitoring, medication administration, and sick-day rules
•
Dietitians: Develop culturally appropriate meal
plans and nutritional counseling
•
Pharmacists: Review medication regimens,
identify drug interactions, and reinforce administration instructions
•
Social workers: Address socioeconomic barriers
to medication access, monitoring supplies, and dietary recommendations
•
Community health workers: Bridge clinical care
with community education, mosque outreach, and culturally concordant support
Bedside
Hack #7: Host "Ramadan Preparation Workshops" 4-6 weeks
pre-Ramadan. These group sessions—led by the multidisciplinary team—cover risk
stratification, medication adjustment, monitoring, nutrition, and patient
testimonials. Group dynamics foster peer support and normalize medical
precautions. Patients learn from each other's experiences. Offer sessions in
multiple languages and provide childcare to maximize accessibility.
Technology and Innovation in Ramadan Diabetes Care
Telemedicine and Remote Monitoring
The COVID-19 pandemic
accelerated telemedicine adoption, with sustained benefits for Ramadan care.
Virtual check-ins during Ramadan—weekly or biweekly—allow real-time medication
titration without requiring clinic visits during fasting hours.
Remote glucose monitoring
platforms (e.g., Dexcom Clarity, LibreView) enable clinicians to review CGM
data and provide feedback asynchronously. Patients upload glucose logs via
smartphone apps, and clinicians adjust regimens through secure messaging.17
Clinical
Pearl #8: Establish a "Ramadan hotline"—a dedicated
phone number or messaging platform where patients can reach a nurse or
physician for urgent questions during fasting hours. Most queries are simple
("My glucose is 75 mg/dL, should I break my fast?") and prevent
unnecessary ER visits or dangerous decisions. Triage protocols empower nurses
to manage routine issues and escalate complex cases.
Mobile Applications
Specialized Ramadan diabetes
apps provide prayer times, iftar/suhoor reminders, medication alerts, and
glucose logging. Some integrate with CGM systems for comprehensive tracking.
While promising, ensure apps are evidence-based and not commercial marketing
tools.
Oyster
#6: Gamification in diabetes apps shows emerging utility. Apps
that reward consistent glucose monitoring with "badges" or
"streaks" leverage behavioral psychology. During Ramadan, when
motivation peaks due to religious commitment, gamified elements can reinforce
positive behaviors. However, avoid apps that penalize missed targets—guilt and
shame undermine adherence.
Cultural Competence: Beyond Clinical Knowledge
Cultural competence is not
cultural proficiency—you need not be Muslim to provide excellent Ramadan
diabetes care. You must, however, demonstrate respect, curiosity, and humility.
Key principles:
•
Ask, don't assume: Not all Muslims fast
identically. Practices vary by sect, culture, and individual interpretation.
Ask patients about their specific Ramadan plans.
•
Use appropriate terminology: "Suhoor"
(pre-dawn meal), "iftar" (fast-breaking meal), "taraweeh"
(evening prayers). Using correct terms signals respect.
•
Acknowledge spiritual significance: Frame
discussions around supporting patients' religious goals, not undermining them.
"I want to help you fast safely" vs. "You shouldn't fast."
•
Involve family: Ramadan is communal. Engage
family members in education—they prepare meals, notice hypoglycemia symptoms,
and provide accountability.
•
Recognize diversity: Muslim communities span
ethnicities, languages, and cultures. Avoid stereotyping. A Bangladeshi
immigrant's Ramadan differs from an Arab-American's.
Bedside
Hack #8: Learn a simple Arabic greeting: "Ramadan
Mubarak" (Blessed Ramadan) or "Ramadan Kareem" (Generous
Ramadan). This small gesture—offered genuinely—builds rapport instantly.
Patients feel seen and respected. Non-Muslim clinicians who make this effort
often inspire greater trust than Muslim clinicians who appear disinterested in
the religious context.
Conclusion
Pre-Ramadan evaluation in
diabetes is a complex, multifaceted clinical challenge demanding medical
expertise, cultural sensitivity, and individualized care. The stakes are
high—hypoglycemia can be life-threatening, yet overly restrictive advice
alienates patients and prompts them to fast without medical guidance,
paradoxically increasing risk.
The principles outlined
here—evidence-based risk stratification, judicious medication adjustment,
intensive monitoring, structured patient education, and culturally competent
communication—form the foundation of safe Ramadan fasting. However, medicine is
art as much as science. Each patient presents unique circumstances requiring
clinical judgment, empathy, and flexibility.
Ultimately, our goal is not
merely glycemic control but holistic well-being. For many patients, successfully
fasting during Ramadan carries profound spiritual meaning, strengthening faith,
community connection, and personal discipline. When we help patients fast
safely, we honor their values while protecting their health. This synthesis of
clinical excellence and cultural respect represents the highest calling of
medicine.
Final
Pearl: The most important intervention is presence. Be
available—before, during, and after Ramadan. Patients who feel supported by
their healthcare team are more likely to monitor diligently, adjust medications
appropriately, and break fasts when medically necessary. Your commitment to
their care validates their effort to balance faith and health. This therapeutic
relationship, more than any algorithm or protocol, ensures meaningful and safe
fasting.
References
1. Pew Research Center. The
Future of World Religions: Population Growth Projections, 2010-2050.
Washington, DC: Pew Research Center; 2015.
2. Hassanein M, Al-Arouj M,
Hamdy O, et al. Diabetes and Ramadan: Practical guidelines. Diabetes Res
Clin Pract. 2017;126:303-316.
3. Salti I, Bénard E, Detournay
B, et al. A population-based study of diabetes and its characteristics during
the fasting month of Ramadan in 13 countries: results of the epidemiology of
diabetes and Ramadan 1422/2001 (EPIDIAR) study. Diabetes Care.
2004;27(10):2306-2311.
4. Ahmedani MY, Haque MS, Basit
A, et al. Ramadan Prospective Diabetes Study: the role of drug dosage and
timing alteration, active glucose monitoring and patient education. Diabet
Med. 2012;29(6):709-715.
5. Beshyah SA, Hassanein M,
Ahmedani MY, et al. Diabetic patients' perceptions and attitudes towards
physicians' advice regarding fasting Ramadan: a survey from the Middle East and
Asia. Diabetes Res Clin Pract. 2019;150:266-272.
6. International Diabetes
Federation (IDF) and Diabetes and Ramadan (DAR) International Alliance.
Diabetes and Ramadan: Practical Guidelines 2021. Brussels: IDF; 2021.
7. Amin ME, Chroinin DN, Brennan
M. Ramadan fasting and diabetes: a narrative review. Ir J Med Sci.
2020;189(2):413-419.
8. Cryer PE. The barrier of
hypoglycemia in diabetes. Diabetes. 2008;57(12):3169-3176.
9. Sinclair AJ, Abdelhafiz AH,
Rodríguez-Mañas L. Frailty and sarcopenia—newly emerging and high impact
complications of diabetes. J Diabetes Complications.
2017;31(9):1465-1473.
10. Shete A, Shaikh A, Nayeem
KJ, et al. Vildagliptin vs sulfonylurea in Indian Muslim diabetes patients
fasting during Ramadan. World J Diabetes. 2013;4(6):358-364.
11. Wan Seman WJ, Kori N, Rajoo
S, et al. Switching from sulphonylurea to a sodium-glucose cotransporter2
inhibitor in the fasting month of Ramadan is associated with a reduction in
hypoglycaemia. Diabetes Obes Metab. 2016;18(6):628-632.
12. Al-Arouj M, Bouguerra R,
Buse J, et al. Recommendations for management of diabetes during Ramadan. Diabetes
Care. 2005;28(9):2305-2311.
13. Alamoudi R, Alsubaiee M,
Alqarni A, et al. Comparison of insulin pump therapy and multiple daily
injections insulin regimen in patients with type 1 diabetes during Ramadan
fasting. Diabetes Technol Ther. 2017;19(7):429-434.
14. Elbarbary NS, Dos Santos TJ,
de Beaufort C, et al. COVID-19 outbreak and pediatric diabetes: Perceptions of
health care professionals worldwide. Pediatr Diabetes.
2020;21(7):1083-1092.
15. Islamic Medical Association
of North America (IMANA) Ethics Committee. Islamic medical ethics: The IMANA
perspective. J IMA. 2005;37:33-42.
16. Mirghani Dirar A, Doupis J.
Gestational diabetes from A to Z. World J Diabetes. 2017;8(12):489-511.
17. Lee JM, Hirschfeld E, Wedding
J. A patient-designed do-it-yourself mobile technology system for diabetes:
promise and challenges for a new era in medicine. JAMA.
2016;315(14):1447-1448.
Conflicts of Interest: The author declares no
conflicts of interest related to this manuscript.
Funding: No external
funding was received for this work.
Correspondence: For
inquiries regarding this review article, please contact the editorial office of
the journal.
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